Tips to keep in mind for Thalassemia in Pregnancy. The organs, which are under stress, are going to have the further demands of developing a baby. What All Risks Can Nulliparous Women Face? 2000. Genetic counseling and genetic testing are recommended for families who carry a thalassemia trait. Pregnancy is a common setting for the diagnosis of β-thalassemia minor or α-thalassemia trait in previously asymptomatic women who are found to be anemic on routine laboratory evaluation during pregnancy. Your use of this site indicates your agreement to be bound by the Terms of Use. Beta thalassemia major increases your chances of having complications for the duration of your pregnancy. You may be recommended to go in for bone marrow transplant. Thalassemia is one such genetic disorder that may get passed on to the baby. However, the following are some of the common treatment options that may be suggested to you by your doctor: Here’s how you will know if your baby will have thalassemia or not: The above-mentioned possibilities remain the same in each case of pregnancy, of the same couple. We shall discuss in detail how a woman may effectively manage your pregnancy if you have thalassemia. The following conditions were significantly associated with beta-thalassemia minor: oligohydramnios (odds ratio [OR] 2.1; 95% confidence interval [CI] 1.2%, 3.7%), intrauterine growth restriction (IUGR; OR 2.4; 95% CI 1.4%, 4.2%), Jewish ethnicity (OR 1.5; 95% CI 1.2%, 1.9%), and previous cesarean delivery (OR 1.4; 95% CI 1.1%, 2.0%). In case you are beta-thalassemia major, which may affect your bones severely; vaginal delivery may become not possible and may require a c-section in the hospital. Intermedia and Minor presentations have some impact on lifestyle and quality of life and are often diagnoses early in life. Though your baby has the same amount of chances to be born with thalassemia major. If you inherit the defective gene from either of your parents. You may require a blood transfusion to ward off anaemia. Also Read: Triple Marker Test During Pregnancy: Why, When & How. Firstly, it was possible by discriminant function analysis of haematological variables to distinguish in pregnant patients between the anaemia caused bythalassaemia trait andthat caused by iron deficiency.  |  Being a carrier of the trait is sometimes known as having the thalassaemia trait or having thalassaemia minor. Thrombotic events include pulmonary embolism, arterial occlusion, portal thrombosis, and deep vein thrombosis. HHS Thalassemia major is usually fatal in the first years of life. Thalassemia in pregnancy may pose some serious complications. USA.gov. The placenta is taken for DNA testing and this test is known as. 2000 Feb;29(1):86-93. If the mother does have the trait, the father is … Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. However, the chances are one in two that your baby is born with thalassemia minor. During the study period there were 159,195 deliveries, of which 261 (0.2%) occurred in patients with beta-thalassemia minor. Some women were diagnosed in pregnancy following anaemia work up. A multivariate logistic regression model, with backward elimination, was constructed to find independent risk factors associated with maternal beta-thalassemia minor. Most women with thalassaemia will also require ovulation induction therapy to achieve pregnancy. I, Levy a, Bashiri A. 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